Toxicological assessment of PEGylated single-walled carbon nanotubes in early developing zebrafish
نویسندگان
چکیده
منابع مشابه
Single - Walled 4 . Single - Walled Carbon Nanotubes
Single-walled carbon nanotubes (SWCNTs) are hollow, long cylinders with extremely large aspect ratios, made of one atomic sheet of carbon atoms in a honeycomb lattice. They possess extraordinary thermal, mechanical, and electrical properties and are considered as one of the most promising nanomaterials for applications and basic research. This chapter describes the structural, electronic, vibra...
متن کاملEvaluation of the Effect of PEGylated Single-Walled Carbon Nanotubes on Viability and Proliferation of Jurkat Cells
Among the numerous nanosized drug delivery systems currently under investigation, carbon nanotubes (CNTs), regardless of being single or multiple-walled, offer several advantages and are considered as promising candidates for drug targeting. Despite the valuable potentials of CNTs in drug delivery, their toxicity still remains an important issue. After the PEGylation of single-walled CNTs ...
متن کاملAquatic toxicity assessment of single-walled carbon nanotubes using zebrafish embryos
Zebrafish embryos selected at the 64-cell stage were exposed to various concentrations of amide functionalized single-walled carbon nanotubes (SWCNTs) ranging from 1 to 10 μg/ml dissolved in 1% Pluronic F-68 (a cell culture grade surfactant), and the development of embryos was examined from 24 to 120 hours post fertilization (hpf). Incubation of embryos in 1% F-68 did not induce overt abnormal ...
متن کاملCutting single-walled carbon nanotubes.
A two-step process is utilized for cutting single-walled carbon nanotubes (SWNTs). The first step requires the breakage of carbon-carbon bonds in the lattice while the second step is aimed at etching at these damage sites to create short, cut nanotubes. To achieve monodisperse lengths from any cutting strategy requires control of both steps. Room-temperature piranha and ammonium persulfate solu...
متن کاملEvaluation of the Effect of PEGylated Single-Walled Carbon Nanotubes on Viability and Proliferation of Jurkat Cells
Among the numerous nanosized drug delivery systems currently under investigation, carbon nanotubes (CNTs), regardless of being single or multiple-walled, offer several advantages and are considered as promising candidates for drug targeting. Despite the valuable potentials of CNTs in drug delivery, their toxicity still remains an important issue. After the PEGylation of single-walled CNTs ...
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ژورنال
عنوان ژورنال: Toxicology and Applied Pharmacology
سال: 2018
ISSN: 0041-008X
DOI: 10.1016/j.taap.2018.03.031